The Handbook On Thalassemia
Thalassemia is a group of inherited hemoglobin disorders characterized by reduced or absent synthesis of one or more globin chains, leading to chronic anemia and significant morbidity if not identified early. Comprehensive and timely screening is essential for effective patient management, genetic counselling and prevention of severe disease through informed clinical and public health interventions.
The TOSOH PROFESSIONAL ASSISTANCE PROGRAM (TPAP) handbook on thalassemia screening has been developed as a comprehensive reference to support healthcare professionals and laboratory specialists in the detection and characterization of thalassemia and related hemoglobinopathies. Leveraging Tosoh’s expertise in high-performance liquid chromatography (HPLC) based hemoglobin analysis, TPAP provides detailed insights into hemoglobin fraction separation, interpretation of chromatographic patterns and differentiation of thalassemia traits from other hemoglobin variants.