TOYOPEARL DEAE-650S

TOYOPEARL DEAE-650S resin is a weak anion exchanger for biomolecule purification. The resin is composed of a base material of hydroxylated methacrylic polymer beads that have been functionalized with diethylaminoethyl (DEAE) weak anion exchange groups.  TOYOPEARL DEAE-650S has a high degree of chemical and mechanical stability, allowing cleaning-in-place (CIP) and high flow rates.

TOYOPEARL DEAE-650S has a 100 nm pore size and a 35 µm bead size and can be used for high resolution intermediate purification and polishing process steps. If greater resolution is needed, the smaller particle TSKgel DEAE-5PW resins may be used. If lower resolution is desired, the larger particle size TOYOPEARL DEAE-650M or TOYOPEARL DEAE-650C resins can be used. As both the TOYOPEARL DEAE-650 and TSKgel DEAE-5PW resins use the same ligand and backbone chemistry, the selectivity between the two resins will be unchanged