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Description

The TSKgel UltraSW Aggregate column is designed with a higher exclusion limit and smaller particle size (3 µm) than the other TSKgel SW mAb columns and is for the high resolution analysis of higher order mAb aggregates.

 

The larger molecular weight exclusion limit of the TSKgel UltraSW Aggregate column allows for superior resolving power for multimers and aggregates of large proteins, including thyroglobulin and IgG.

Specifications

Pore Size (nm)
30
Applications
mAb fragments, Monoclonal antibodies, Aggregates
Column Length (cm)
30
Housing Material
Stainless Steel
Base Material
Silica
Group
SW mAb
Mode
Aqueous Size Exclusion - GFC
Product Category
HPLC Columns
Particle Size (µm)
3
Column Diameter (mm)
7.8

Resources

Separation of a Monoclonal Antibody Monomer from its Impurities using New TSKgel SW mAb Columns
Analysis of Monoclonal Antibody and Protein Aggregates Induced by Denaturation using a Novel Size Exclusion Chromatography Column
Improving Recovery and Resolution of mAb Aggregates using Mobile Phase Additives in SEC
Analysis of Monoclonal Antibody Aggregates by SEC using MS-Friendly Mobile Phases
Monitoring Protein Unfolding and Refolding
TSKgel SW mAb Products
TSKgel Column Instruction Manual
TSKgel U/HPLC Columns 2019 Product Guide -- SEC, SW Series Columns
TSKgel SuperSW mAb HR, TSKgel SuperSW mAb HTP and TSKgel UltraSW Aggregate Columns
New silica-based SEC columns designed for the separation of mAb monomers and their impurities
Three novel prototype SEC columns for the separation of an antibody monomer from its dimer, higher aggregates, and antibody fragments
Three novel prototype silica-based SEC columns designed for the separation of an antibody monomer from its dimer, higher aggregates, and antibody fragments
Detection of protein heterogeneity by HPLC (additional data included)
Three Novel Size Exclusion Chromatography Columns Designed for the Separation of a Monoclonal Antibody Monomer from its Impurities
Separation of Proteins and Monoclonal Antibodies using New Wide Pore C4 Phase Silica Gel Reversed Phase Column with Moderate Hydrophobicity Designed for Protein Separation
Separation of Proteins with a Wide Variety of Hydrophobicity using a Reversed Phase 30 nm Pore Size Short Alkyl Chain Column
Characterization of Two Novel Analytical Chromatographic Columns for Orthogonal Analysis of Monoclonal Antibodies and Protein Aggregates and Their Isoforms
Separation of Monoclonal Antibody and Protein Aggregates Induced by Thermal Denaturation, using a Novel Size Exclusion Chromatography Column
Stability Studies of a Novel Silica-Based, Diol-Bonded Size Exclusion Chromatography Analytical Column Specifically Designed for the Separation of Aggregates
Use of 3 μm Analytical Size Exclusion Chromatography (SEC) Column for Monitoring Protein Unfolding and Refolding in Stability Studies of Proteins and Monoclonal Antibodies
Effect of Larger Exclusion Limit on the Separation of HMW Species – a Study Using a 3 μm Size Exclusion Chromatography Column

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