TSKgel BioAssist S

Specially designed for the separation of large biomolecules such as antibodies, the large pores (130 nm) of the TSKgel BioAssist S cation exchange columns offer superior capacity and resolution at a low column pressure drop. Constructed via a polymerization technique that allows an equivalent density of sulfopropyl ionic exchange groups to be incorporated into the particle without reducing pore size, the TSKgel BioAssist S columns are unlike other ion exchange columns that use graft polymerization for polymer chain introduction. The TSKgel BioAssist S columns’ large pores are very accessible even for high molar mass proteins. This leads to higher chromatographic efficiency and binding capacity for purification.

The standard TSKgel BioAssist S column is 4.6 mm ID x 5 cm, while a 10 mm ID x 10 cm semi-preparative column is available for scale-up. Both columns are made of PEEK to reduce protein adsorption.