Precision Medicine In The Allergy Clinic: The Application Of Component Resolved Diagnosis
A precise diagnosis is key for the optimal management of allergic diseases and asthma. In-vivo or in-vitro diagnostic methods that use allergen extracts often fail to identify the molecules eliciting the allergic reactions. Component Resolved Diagnostics (CRD) has become a very important tool in precision allergen diagnosis. Currently, there is a wide range of options available as singleplex or multiplex platforms using purified or recombinant allergens to yield patient sensitization profiles.
CRD has solved most of the limitations of extract-based diagnostic procedures and is currently valuable tool for the precision diagnosis in the allergy clinic, for venom and food allergy, asthma, allergic rhinitis and atopic dermatitis. This approach facilitates the identification of the major sensitizers, cross-reactive allergens, the evaluation of risk to develop severe reactions, the selection of patients benefiting most from AIT and monitoring its efficacy.
The diagnostic strategy based on CRD is part of the new concept of precision immunology, which aims to improve the management of allergic diseases.
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Precision Medicine In The Allergy Clinic: The Application Of Component Resolved
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