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Gel filtration chromatography (aqueous SEC)

TSKgel Gel Filtration Chromatography ColumnsGel Filtration Chromatography (GFC) is popular among biochemists for the separation of proteins or nucleic acid fractions, to desalt a protein sample, or to characterize water-soluble polymers used in food ...
Education

EcoSEC High Temperature GPC System

EcoSEC High Temperature SystemDemanding high temperature polymer analyses, such as for polyolefins, require a system that delivers results reliably, reproducibly, and produces these results in an easy to use, safe instrument. The EcoSEC High Temperat...
Education

HIC columns – what they do and how to find the right one

HIC columns – hydrophobic interaction chromatography for (U)HPLC analysisHydrophobic interaction chromatography (HIC) is a technique that separates molecule mixtures according to their hydrophobicity. It is popular for analyzing and purifying protein...
Education

Cation Exchange

TSKgel Cation Exchange Chromatography ColumnsVery efficient chromatography can be achieved with the nonporous TSKgel STAT columns due to the novel bonding chemistry and the absence of micro-pores. Applications for the TSKgel CM-STAT and TSKgel SP-STA...
Education

Lens3 MALS Detector

LenS3 Multi-Angle Light Scattering DetectorsThe next generation of LenS™3 MALS detector provides the latest in light scattering detection from Tosoh Bioscience. Technological advancements in instrument design and software simplify exact molecular wei...
Education

Products

SolutionsThis Solutions section is designed to help you learn about the theory and practice of liquid chromatography to aid you in selecting the best Tosoh product for your application. The section is organized by product group and contains an overvi...
Education

Chromatography instruments

As an expert in chromatography solutions, Tosoh Bioscience offers chromatography equipment that allows you to achieve the best results for your chromatographic applications.GPC instruments – all-in-one solution for polymer analysisEcoSEC is a compact...
Education

Hydrophilic Interaction Chromatography - Columns

Hydrophilic Interaction ChromatographyNormal phase and hydrophilic interaction liquid chromatography (HILIC) are primarily used to separate polar and hydrophilic compounds. In reversed phase mode very polar compounds are often not sufficiently retain...
Education

Anion Exchange - Columns

Very efficient chromatography can be achieved with the nonporous TSKgel STAT columns due to the novel bonding chemistry and the absence of micro-pores. Applications for the TSKgel Q-STAT columns include the separation of: proteins, peptides, low mole...
Education

MCC Applications

The Octave TM systems can be used for a variety of applications, including:Intensified chromatography unit operationIntegrated continuous processingParallel batch chromatographySimulated moving bedList of MCC ApplicationsYearTitleAuthors  Journa...
Education

Benefits of MCC

Multi-column chromatography results in higher productivity due to higher load levels, faster flowrates, and parallelization of non-loading steps.Multi-column chromatography provides the following benefitsReduced resin consumption (cost savings)Increa...
Education

Holistic Multi-Column Chromatography Solution

Multi-column chromatography is a liquid chromatographic technique used to purify solutions via a cyclic usage of multiple columns that is faster and more cost-effective than batch chromatography.The OctaveTM MCC platform is designed to purify biomole...
Education

Introduction to the Multi-Column technique

MCC can be run continuously and intensifies the chromatography step, compared to batch chromatography.Compared to an injection of a distinct sample volume onto a comparably large column as done in classic batch- or single-column chromatography, MCC t...
Education

Multi-column chromatography (MCC)

Multi-column chromatography (MCC) is an innovative downstream processing (DSP) method for the purification of biological targets.MCC can be run continuously and intensifies the chromatography step, compared to batch chromatography. This is accomplish...
Articles

Early sepsis diagnosis using Presepsin

Validation of AIA-360 for Determination of Presepsin: A Useful Tool for the Diagnosis of Sepsis at the Emergency Department Sepsis is a systemic syndrome, originally conceptualized as the decomposition of animal or vegetable matter in the presen...
Articles

Clinical and technical advantages of CRD

Precision Medicine In The Allergy Clinic: The Application Of Component Resolved DiagnosisA precise diagnosis is key for the optimal management of allergic diseases and asthma. In-vivo or in-vitro diagnostic methods that use allergen extract...
Videos

AIA-360

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Articles

Reliable HbA1c results using HLC-723GX

Analytical verification and quality assessment of the Tosoh HLC-723GX HbA1C analyzer HbA1C assay has been established as the cornerstone of diabetes care for decades. Advances in methodology and global standardization of HbA1C assays h...
Videos

World Diabetes Day

Tosoh Bioscience Announces GPC Glossary and Column Selection Mobile App

King of Prussia, PA  -  Tosoh Bioscience LLC announces the availability of the GPC Glossary and Column Selection Guide app, which offers easy access to 200 Gel Permeation Chromatography (GPC) terms and a GPC column selection wizard for prec...

BioProcessing Summit US

Mastering MCC: From Fundamentals to Process Scale

Chromatography in Process Development & Production

Optimizing Protein Purification: Key Tips for Process Efficiency

In today’s biopharmaceutical industry, efficient protein purification is essential for delivering high-quality therapeutic products. Selecting the right chromatography resins and optimizing process conditions can significantly improve yield, purity, ...
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