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Selected Diagnostics-IND- Product- AIA-BMG
Diagnostics-IND- Product- AIA-BMG

Description

Human BMG is a single polypeptide that is shed from the cell membrane of all nucleated cells. In general, BMG can easily pass the glomerular basement membrane and in the renal tubule most of it is reabsorbed and catabolized. Therefore, when reabsorption by the renal tubule is hindered, a large amount of BMG is excreted in urine. On the other hand if glomerular filtration rate (GFR) is reduced, the level of BMG in the blood increases, making it possible to differentiate the two diseases. The level of urinary BMG is elevated in diseases such as heavy metal poisoning, Fanconi syndrome and Wilson’s disease, while the level of serum BMG is elevated in diseases such as chronic nephritis, nephrotic syndrome, malignant tumor and autoimmune disease. BMG assay has been applied to the diagnosis, monitoring and prognostication of these diseases.

Technical specifications

Kit nameST AIA-PACK BMG
MethodEnzyme Immunoassay (EIA)
Assay principleTwo-site immunoenzymometric assay
Assay sampleSerum, heparinized plasma or urine
Calibrators0, 0.0125, 0.05, 0.15, 0.30, 0.42 mg/L
Standardization Internal
Calibration stability90 days
Assay rangeSerum, heparinized plasma (51 times dilution): 0.1 - 20 mg/L 
Urine (5 times dilution): 0.1 - 2 mg/L 
Reaction time10 minutes
Hook effectSerum / plasma: >102 mg/L, Urine: >10 mg/L
Storage2 - 8oC

 

 

 

 

 

 

 

 

 

 

 

 

Refer to the product Instruction-For-Use (IFU) for complete details.

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