ST AIA-PACK HCGII

Human Chorionic Gonadotropin (hCG) is a glycoprotein hormone which is synthesized and secreted on placental villi and it is considered a good indicator of placental function. Structurally, hCG consists of two subunits; α and β , which are bound by a non-covalent bond. While the amino acid sequence of the α-subunit of hCG is the same as that of the α-subunit of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH) and luteinizing hormone (LH), which are secreted from the anterior pituitary gland but the β-subunit of these hormones is unique to each. However, the β-subunit of hCG and that of LH have a high degree of homology in amino acid sequence, and the distinct difference between these two hormones is in C-terminal 30 amino acids (CTP). hCG is produced by the placenta shortly after implantation and increases at a geometric rate until it reaches a peak near the end of the first trimester. This makes it an excellent marker for the confirmation of pregnancy and/or monitoring its thereafter when necessary. Other conditions associated with elevated serum hCG concentrations are neoplasm's of trophoblastic and non-trophoblastic origin.

Technical specifications

Refer to the product Instruction-For-Use (IFU) for complete details.