ST AIA-PACK Intact PTH

Parathyroid hormone (PTH) raises blood ionized calcium levels by promoting bone resorption and releasing calcium and phosphate from the bone to the extracellular fluid through direct action on bone. PTH also promotes reabsorption of ionized calcium and inhibit the renal reabsorption of phosphate through the action on renal tubular. PTH is rapidly metabolized in the liver and kidney to primarily biological active N-terminal and biological inactive C-terminal fragment with much longer half lives. Intact PTH assays accurately reflect PTH-secretion kinetics because of being less influenced by the declining renal function. Therefore, intact PTH is a valuable marker to find the diseases of the parathyroid gland and the kidney to judge success or failure of operation removing malignant parathyroid gland and to observe post-operative recovery.

Technical specifications

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