
ST AIA-PACK IRI is designed for in-vitro
Part #: 0025260
Manufacturers:
Insulin is the antidiabetic hormone produced by the pancreatic B cell as a large proinsulin (containing of 109 amino acids). This peptide is rapidly converted by cleavage to proinsulin (containing of 86 amino acids). Equimolar quantities of insulin and C-peptide are produced through proteolytic cleavage and then secreted along with a small amount of proinsulin. In certain clinical types of diabetes, autologous insulin secretion is basically non-existent or defective and in these cases, the level of glucose is naturally elevated. The state of insulin secretion is ascertained by measuring the level of IRI with time as oral glucose tolerance test (OGTT). On the other hand, in the case of fasting hypoglycemia, insulin assay is important for identifying the cause and is used for the diagnosis of insulinoma (pancreatic islet tumor).
Technical specifications
| Kit name | ST AIA-PACK IRI |
| Method | Enzyme Immunoassay (EIA) |
| Assay principle | Two-site immunoenzymometric assay |
| Assay sample | Serum, heparinized plasma or EDTA plasma |
| Calibrators | 0, 20, 40, 80, 160, 340 mU/mL |
| Standardization | WHO 1st IRP 66/304 |
| Calibration stability | 90 days |
| Assay range | 0.5 - 320 mU/mL |
| Reaction time | 10 minutes |
| Hook effect | >20,000 mU/mL |
| Storage | 2 - 8oC |
Refer to the product Instruction-For-Use (IFU) for complete details.