ST AIA-PACK Myoglobin

Myoglobin is an oxygen-binding heme protein of low molecular weight found in both cardiac and skeletal muscle. Myoglobin is released from the muscle cells and appears in the circulation after injury to the skeletal muscles or myocardium (e.g. acute myocardial infarction or AMI), surgery, exercise or myopathies. In AMI, damaged myocardial tissue leads to elevated myoglobin above normal levels within 2-3 hours after onset of symptoms, reaching peak levels at 6 to 9 hours and returning to the normal level by 24 hours. The rapid elevation of myoglobin in the circulation has lead to its usefulness for the early diagnosis and monitoring of AMI. Increase in myoglobin concentration following thrombolytic treatment act as an early predictor of infarct reperfusion. Successful reperfusion of a blocked coronary artery is indicated by myoglobin levels which peak between 30 minutes and 2 hours following thrombolytic therapy. 

Technical specifications

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