ST AIA-PACK PRL

Prolactin (PRL) is secreted from anterior pituitary gland and acts directly on the mammary gland to stimulate milk production. When secreted in excess, it increases adrenal androgens and blunts the response of gonadotropes and gonadal cells to tropic factors by decreasing gonadoliberin. Thus, chronically elevated prolactin induces ammenorrhea and infertility in women and impotence in men. Prolactin synthesis and secretion in under inhibitory control by the hypothalamus. Dopamine is established as the hypothalamic prolactin inhibiting factor (PIF). Measurement of prolactin concentration in blood is essential in evaluating patients with infertility or suspected hypothalamic-pituitary dysfunction. Increased serum prolactin concentrations are observed in pregnancy in pregnancy and during lactation.

Technical specifications

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