ST AIA-PACK TgAb

Anti-thyroid antibodies, especially anti-microsomal antibodies and anti-thyroglobulin antibodies (TgAb) have been shown to be relevant to autoimmune thyroid disease such as Graves’ disease and Hashimoto’s disease. However, TgAb sometimes tests positive for auto-immune diseases other than those involving the thyroid, so the disease specificity of TgAb is not clear. Thyroglobulin (Tg) is a protein that has a molecular weight of about 660 kDa. It is synthesized in thyroid gland cells and is the main component of the colloid contained in the thyroid follicles. Tg plays an important role in the synthesis and preservation of thyroid hormones. Although TgAb has conventionally been assayed by semi-quantitative methods using indirect agglutination, highly sensitive quantitative methods such as the RIA and EIA methods have been developed. AIA-PACK TgAb is an enzyme immunoassay reagent to measure concentrations of TgAb in human serum or heparinized plasma using Tg antigen-coated beads and mouse anti-human IgG monoclonal antibody labeled with alkaline phosphatase.

Technical specifications

Refer to the product Instruction-For-Use (IFU) for complete details.