
ST AIA-PACK TPOAb is intended for in-vitro diagnostic use for the quantitative measurement of anti-thyroid peroxidase antibodies (TPOAb) in human serum or heparinized plasma on TOSOH AIA systems.
Part #: 0020290
Manufacturers:
Anti-thyroid antibodies, especially anti-microsomal antibodies and anti-thyroglobulin antibodies have been shown to be relevant to autoimmune thyroid disease such as Graves’ disease and Hashimoto’s disease. For the detection of the anti-microsomal antibodies, some methods based on the thyroid microsomal fraction-coated cell or particles were available. Recently, the major component of the antigen recognized by the anti-microsomal antibodies was identified as the thyroid peroxidase (TPO). The findings have led to some sensitive and specific assays for the anti-microsomal antibodies that are anti-TPO antibodies (TPOAb) using TPO antigen. AIA-PACK TPOAb is an enzyme immunoassay reagent to measure concentrations of TPOAb in human serum or heparinized plasma using TPO antigen-coated beads and mouse anti-human IgG monoclonal antibody labeled with alkaline phosphatase.
Technical specifications
| Kit name | ST AIA-PACK TPOAb |
| Method | Enzyme Immunoassay (EIA) |
| Assay principle | Two-site immunoenzymometric assay |
| Assay sample | Serum or heparinized plasma |
| Calibrators | 0, 0.5, 2, 4, 10, 23 IU/mL |
| Standardization | NIBSC code 66/387 |
| Calibration stability | 90 days |
| Assay range | 0.05 – 20 IU/mL |
| Reaction time | 10 minutes |
| Storage | 2 - 8oC |
Refer to the product Instruction-For-Use (IFU) for complete details.