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Selected Diagnostics-IND- Product-ExtraAIA2
Diagnostics-IND- Product-ExtraAIA2

Description

Anti-thyroid antibodies, especially anti-microsomal antibodies and anti-thyroglobulin antibodies have been shown to be relevant to autoimmune thyroid disease such as Graves’ disease and Hashimoto’s disease. For the detection of the anti-microsomal antibodies, some methods based on the thyroid microsomal fraction-coated cell or particles were available. Recently, the major component of the antigen recognized by the anti-microsomal antibodies was identified as the thyroid peroxidase (TPO). The findings have led to some sensitive and specific assays for the anti-microsomal antibodies that are anti-TPO antibodies (TPOAb) using TPO antigen. AIA-PACK TPOAb is an enzyme immunoassay reagent to measure concentrations of TPOAb in human serum or heparinized plasma using TPO antigen-coated beads and mouse anti-human IgG monoclonal antibody labeled with alkaline phosphatase.

Technical specifications

Kit nameST AIA-PACK TPOAb
MethodEnzyme Immunoassay (EIA)
Assay principleTwo-site immunoenzymometric assay
Assay sampleSerum or heparinized plasma
Calibrators0, 0.5, 2, 4, 10, 23 IU/mL
Standardization NIBSC code 66/387
Calibration stability90 days
Assay range0.05 – 20 IU/mL
Reaction time10 minutes
Storage2 - 8oC

 

 

 

 

 

 

 

 

 

 

 

Refer to the product Instruction-For-Use (IFU) for complete details.

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