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Selected SEP Prod TOYOPEARL Bottles Group 100 250 1000 mL
SEP Prod TOYOPEARL Bottles Group 100 250 1000 mL

Description

TOYOPEARL SP-650C resin is a strong cation exchanger for biomolecule purification. The resin is composed of a base material of hydroxylated methacrylic polymer beads that have been functionalized with sulfopropyl (S) strong cation exchange groups.  TOYOPEARL SP-650C resin has a high degree of chemical and mechanical stability, allowing cleaning-in-place (CIP) and very high flow rates. TOYOPEARL SP-650C resin has a 100 nm pore size and a 100 µm bead size.

TOYOPEARL SP-650C resin can be used for high throughput capture, intermediate purification, and polishing process steps. If greater resolution is needed, the smaller particle TSKgel SP-5PW resins may be used. As both the TOYOPEARL SP-650C and TSKgel SP-5PW resins use the same ligand and backbone chemistry, the selectivity between the two resin types will be unchanged.

TOYOPEARL SP-650C resin has a dynamic binding capacity for lysozyme of 45 g/L. TOYOPEARL SP-650C resin maintains capacity at increased linear velocities, has good pressure-flow characteristics, and will withstand back pressures up to 0.3 MPa.  

Specifications

Particle Size (µm)
100
Pore Size (nm)
100
Process Step
Capture
Resin Volume
1 L, 250 mL, 5 L
Mode
Cation Exchange
Applications
Other recombinant proteins, Enzymes, Aggregates, mAb fragments, Peptides, Monoclonal antibodies, Lipoproteins, Proteins
Product Category
Process Media
Group
Specialty

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