TOYOPEARL CM-650C
Brand: TOYOPEARL
Manufacturers:
Description
TOYOPEARL CM-650C resin is a weak cation exchanger for biomolecule purification. The resin is composed of a base material of hydroxylated methacrylic polymer beads that have been functionalized with carboxymethyl (CM) weak cation exchange groups. TOYOPEARL CM-650C has a high degree of chemical and mechanical stability, allowing cleaning-in-place (CIP) and very high flow rates.
TOYOPEARL CM-650C has a 100 nm pore size and a 100 µm bead size and can be used for high throughput capture, intermediate purification, and polishing process steps. If greater resolution is needed, the smaller particle TOYOPEARL CM-650M or TOYOPEARL CM-650S resins may be used.
TOYOPEARL CM-650C has a dynamic binding capacity for lysozyme of 35 g/L. TOYOPEARL CM-650C maintains capacity at increased linear velocities, has good pressure-flow characteristics, and will withstand back pressures up to 0.3 MPa.
Specifications
| Mode | Cation Exchange |
|---|---|
| Particle Size (µm) | 100 |
| Pore Size (nm) | 100 |
| Process Step | Capture |
| Applications | Aggregates, Proteins, Peptides, Monoclonal antibodies, mAb fragments, Other recombinant proteins, Enzymes, Lipoproteins |
| Group | Specialty |
| Product Category | Process Media |
| Resin Volume | 1 L, 5 L, 50 L, 250 mL |