TOYOPEARL GigaCap DEAE-650M
TOYOPEARL GigaCap DEAE-650M media is a high capacity anion exchange resin optimized for the purification of proteins, including monoclonal antibodies.
Brand: TOYOPEARL
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Description
TOYOPEARL GigaCap
DEAE-650M media is a high capacity anion exchange resin optimized for the
purification of proteins, including monoclonal antibodies. The resin is composed of a base material
of hydroxylated methacrylic polymer beads that have been chemically modified to provide a higher
number of anionic binding sites and functionalized with diethyl amino ethyl (DEAE) weak anion exchange groups.
TOYOPEARL GigaCap DEAE-650 resin can be used for high throughput capture
and intermediate purification of blood products and other proteins. TOYOPEARL
GigaCap DEAE-650 resin is available in one particle size, 75 µm, which
corresponds to the M-grade designation.
TOYOPEARL GigaCap
DEAE-650M exhibits typical dynamic binding capacities > 156 g/L
for BSA, maintains high capacity at increased linear velocities, has good
pressure-flow characteristics, and will withstand back pressures up to 0.3 MPa.
TOYOPEARL GigaCap DEAE-650M also has excellent binding and elution kinetics,
which results in a more concentrated protein fraction collected during the
elution step.
Specifications
| Mode | Anion Exchange |
|---|---|
| Particle Size (µm) | 75 |
| Pore Size (nm) | 100 |
| Process Step | Capture |
| Applications | Vaccines, Virus, Peptides, DNA/RNA, Plasma purification, Proteins, Endotoxins, mAb fragments |
| Group | Specialty |
| Product Category | Process Media |
| Resin Volume | 100 mL, 250 mL, 5 L, 50 L, 1 L |