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Process Media for Purification

Process ChromatographyChromatography is a common purification step in industrial downstream processing (DSP) of biological targets. A typical DSP scheme combines two or more chromatographic separation steps with ultra- and diafiltration unit operatio...
Education

Hydrophilic Interaction Chromatography - Columns

Hydrophilic Interaction ChromatographyNormal phase and hydrophilic interaction liquid chromatography (HILIC) are primarily used to separate polar and hydrophilic compounds. In reversed phase mode very polar compounds are often not sufficiently retain...
Education

Anion Exchange - Columns

Very efficient chromatography can be achieved with the nonporous TSKgel STAT columns due to the novel bonding chemistry and the absence of micro-pores. Applications for the TSKgel Q-STAT columns include the separation of: proteins, peptides, low mole...
Education

MCC Applications

The Octave TM systems can be used for a variety of applications, including:Intensified chromatography unit operationIntegrated continuous processingParallel batch chromatographySimulated moving bedList of MCC ApplicationsYearTitleAuthors  Journa...
Education

Benefits of MCC

Multi-column chromatography results in higher productivity due to higher load levels, faster flowrates, and parallelization of non-loading steps.Multi-column chromatography provides the following benefitsReduced resin consumption (cost savings)Increa...
Education

Holistic Multi-Column Chromatography Solution

Multi-column chromatography is a liquid chromatographic technique used to purify solutions via a cyclic usage of multiple columns that is faster and more cost-effective than batch chromatography.The OctaveTM MCC platform is designed to purify biomole...
Education

Introduction to the Multi-Column technique

MCC can be run continuously and intensifies the chromatography step, compared to batch chromatography.Compared to an injection of a distinct sample volume onto a comparably large column as done in classic batch- or single-column chromatography, MCC t...
Education

Multi-column chromatography (MCC)

Multi-column chromatography (MCC) is an innovative downstream processing (DSP) method for the purification of biological targets.MCC can be run continuously and intensifies the chromatography step, compared to batch chromatography. This is accomplish...
Education

Pre-packed Chromatography Columns

Pre-packed chromatography columns for purification are ready-to-use, available with different kinds of chromatography resins. Sizes range from milliliter scale for screening and method development up to tens of liters for GMP manufacturing. The colum...
Education Experts in Chromatography

Ion Exchange Chromatography

 Ion Exchange Chromatography (IEC or IEX) is driven by interactions between charged target molecules and charged immobilized ligands on the chromatography resin. IEX can be divided into two different sub types. Cation exchange chromatography, in...
Experts in Chromatography Education

SEC columns – the tool for size exclusion chromatography

All chromatography columns that separate mixtures of molecules by size are SEC columns. They consist of a column housing filled with porous particles that are responsible for the retention of molecules of different sizes contained in a sample and thu...
Events

Nov 12, 2025: Chromatography Workshops - Mastering MCC: From Fundamentals to Process Scale

Chromatography WorkshopsMastering MCC: From Fundamentals to Process ScaleThis workshop is designed for downstream processing scientists with little or no prior experience in Multi-Column Chromatography (MCC). Through a highly interactive short course...
Events

Sept 15-18, 2025: BioProcess International East (BPI)

BioProcess International East returns to Boston, MA, for another exciting conference focusing on recent advancements in downstream bioprocessing. The biggest names in Biopharma will unite with Biotech vendors to streamline DSP, and Tosoh Bioscience i...

Tosoh Bioscience Announces GPC Glossary and Column Selection Mobile App

King of Prussia, PA  -  Tosoh Bioscience LLC announces the availability of the GPC Glossary and Column Selection Guide app, which offers easy access to 200 Gel Permeation Chromatography (GPC) terms and a GPC column selection wizard for prec...

BioProcessing Summit US

Mastering MCC: From Fundamentals to Process Scale

Chromatography in Process Development & Production

Optimizing Protein Purification: Key Tips for Process Efficiency

In today’s biopharmaceutical industry, efficient protein purification is essential for delivering high-quality therapeutic products. Selecting the right chromatography resins and optimizing process conditions can significantly improve yield, purity, ...
Education Experts in Chromatography

A Closer Look at Size Exclusion Chromatography (SEC) in Bioprocessing

July 16, 2025

Unleashing the Power of Size Exclusion Chromatography (SEC) in BioprocessingSize Exclusion Chromatography (SEC), also known as gel filtration chromatography, is a cornerstone technique in the biopharmaceutical industry, prized for its ability to sepa...
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